5,014 research outputs found

    Fitness acuático: una alternativa a las gimnasias de mantenimiento

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    En nuestros días, la creciente demanda social ha obligado a las instituciones, públicas y privadas, a incrementar la oferta de actividades físicas en general y por tanto, de las actividades acuáticas relacionadas con la condición física, en particular. La justificación de esta aparición de programas relacionados con la condición física son, por un lado, el continuo aumento de la utilización del tiempo libre en el entorno familiar orientado a la práctica de la actividad física grupal diversa y, por otro lado, los cambios que se observan en la concepción de la actividad física de la población. Estas afirmaciones han posibilitado el surgimiento de las actividades acuáticas relacionadas con la condición física, entendidas en este artículo bajo el concepto de "fitness acuático", las cuales tienen un carácter creativo, de diversión, de distracción y de variada forma de participación. El fitness acuático se encuentra en boga en nuestra sociedad; pero para que este sea tratado ampliamente, es preciso analizarlo desde el punto de vista de la intervención de los técnicos acuáticos, de los medios a utilizar y de los equipamientos necesarios para su realización

    Environmental attitudes of European tourists: A multilevel analysis

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    Literature shows that heterogeneity in willingness to pay for traveling is explained by regional clusters because not all the tourists are equally sensitive to income and price adjustments. This paper demonstrated that such heterogeneity in tourist behavior is also shown in environmental considerations when they are making decisions about their holiday plans. Popular support for environmental protection among tourists from EU-27 countries were investigated. The findings are congruent with the hypothesis that environment support depends not only on individual characteristics of themselves but also of certain contextual variables related to their place of residence.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Explaining tourists´ support for environmental protection

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    Any movement towards sustainable tourism is dependent not only upon the industry and other key stakeholders but also the demand side, namely the tourists. Yet, there is a limited literature from the demand point of view. In this area, contributions to an understanding of tourists’ support to sustainable development are necessary. This paper analyzes the main determinants in tourist behavior regarding the environmental considerations when they are making decisions about their holiday plans. General literature on this issue highlights the need to consider socio-economic variables of the individual as well as the attributes related of their style of living. If the econometric model takes into account all these variables simultaneously, then the linkage between contextual changes and tourists´ behaviour is enriched and it may be estimated more accurately. In this sense, a multilevel approach using a random-intercept logistic models is proposed, since tourists belong to a country are affected by the same contextual variables. The analysis comprises a joint dataset composed by microdata belong to the survey Attitudes of Europeans Towards Tourism, which corresponds to Flash Eurobarometer 281, macrodata from Eurostat (GDP in pps and GDP growth) and additional variables profiles from the 2005 Environmental Sustainability Index. Country-specific effects are calculated across the EU-27 countries, which corroborated that attitudes to the sustainable tourism are heterogeneous geo-graphically. The higher the level of GDP, the lower the level of tourists´ support. These results could be explained because tourists of richer countries already have to pay more tax for envi-ronmental protection. Age, gender and educational attainment are relevant. Motivations for travelling, size of the community, type of the destination, and environmental sustainability indi-cators of the place of residence are also important factors.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Preclinical discovery of duloxetine for the treatment of depression

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    Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases are associated with poor treatment outcomes. From the emergence of the monoamine hypothesis of depression, the first-line treatment for MDD had mainly acted by inhibiting monoamine reuptake, and thereby increasing these levels in the synaptic cleft. However, in recent years, several newantidepressant drugs have appeared, including duloxetine, a dual serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor recommended for the treatment of MDD. Areas covered: The article reviews and discusses the biochemical and functional profile of duloxetine splitting the review into acute and long-term treatment with this dual monoamine reuptake inhibitor. In addition, the authors summarize available preclinical behavioral research data, which have demonstrated among other effects, the antidepressant-like activity of duloxetine in several animal models. The authors focus on the most recent literature on synaptic neuroplasticity modulation of this antidepressant drug. Finally, the authors briefly mention other approved indications of duloxetine. Expert opinion: Duloxetine inhibits 5-HT and NA reuptake, effectively desensitizes various autoreceptors and promotes neuroplasticity. Clinically, duloxetine is an effective antidepressant that is well tolerated and has significant efficacy in the treatment of MDD. associated with poor treatment outcomes. From the emergence of the monoamine hypothesis of depression, the first-line treatment for MDD had mainly acted by inhibiting monoamine reuptake, and thereby increasing these levels in the synaptic cleft. However, in recent years, several new antidepressant drugs have appeared, including duloxetine, a dual serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor recommended for the treatment of MDD

    Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence

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    Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently prescribed to treat this pathology. Yet, many patients are refractory to the available therapeutic drugs, which mainly act by increasing the levels of the monoamines serotonin and noradrenaline in the synaptic cleft. Even in the cases antidepressants are effective, it is usually observed a delay of a few weeks between the onset of treatment and remission of the clinical symptoms. Additionally, many of these patients who show remission with antidepressant therapy present a relapse of depression upon treatment cessation. Thus research has focused on other possible molecular targets, besides monoamines, underlying depression. Both basic and clinical evidence indicates that depression is associated with several structural and neurochemical changes where the levels of neurotrophins, particularly of brain-derived neurotrophic factor (BDNF), are altered. Antidepressants, as well as other therapeutic strategies, seem to restore these levels. Neuronal atrophy, mostly detected in limbic structures that regulate mood and cognition, like the hippocampus, is observed in depressed patients and in animal behavioural paradigms for depression. Moreover, chronic antidepressant treatment enhances adult hippocampal neurogenesis, supporting the notion that this event underlies antidepressants effects. Here we review some of the preclinical and clinical studies, aimed at disclosing the role of neurotrophins in the pathophysiological mechanisms of depression and the mode of action of antidepressants, which favour the neurotrophic/neurogenic hypothesis

    Entre la posmodernidad y el homoerotismo: la imaginería procesional del siglo XXI y el neobarroco gay

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    La teoría del neobarroco gay se corresponde con un lenguaje estético que postula la exaltación del homoerotismo masculino, explícito o sutil, en clave manifiestamente morbosa y en un contexto religioso específico, aplicado a la escultura procesional de finales del siglo XX y lo que llevamos del XXI, donde además se ha tergiversado la construcción social del género en el hombre/escultura. Este proceso coincide con un espacio/tiempo donde se ha producido una creciente aceptación social de la homosexualidad masculina y su visibilidad, además de una evidente puesta en valor de la misma a través de obras donde el cuerpo del hombre sintoniza con su consideración actual como “objeto” de consumo dentro de los medios de masas.Theory of the called “Gay Neobaroque” is an aesthetic language which promotes exaltation of homoerotic and diseased senses applied to sculptural representation of men, in the particular religious context of Spanish sacred imaginery made for celebrations of Holy Week since the end of XX century to the present days and also twisting social construction of “genus” by the man/sculpture because. The called “Gay Neobaroque” is situated on specific space and time with a specific relationships with visibility, value and acceptance of masculine homosexuality and conversion of men´s body in “object” for consumers according rudiments of marketing and motif for publicity and audio-visual and artistic creation

    Application of Deadlock Risk Evaluation of Architectural Models

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    Software architectural evaluation is a key discipline used to identify, at early stages of a real-time system (RTS) development, the problems that may arise during its operation. Typical mechanisms supporting concurrency, such as semaphores, mutexes or monitors, usually lead to concurrency problems in execution time that are difficult to be identified, reproduced and solved. For this reason, it is crucial to understand the root causes of these problems and to provide support to identify and mitigate them at early stages of the system lifecycle. This paper aims to present the results of a research work oriented to the development of the tool called ‘Deadlock Risk Evaluation of Architectural Models’ (DREAM) to assess deadlock risk in architectural models of an RTS. A particular architectural style, Pipelines of Processes in Object-Oriented Architectures–UML (PPOOA) was used to represent platform-independent models of an RTS architecture supported by the PPOOA –Visio tool. We validated the technique presented here by using several case studies related to RTS development and comparing our results with those from other deadlock detection approaches, supported by different tools. Here we present two of these case studies, one related to avionics and the other to planetary exploration robotics. Copyright © 2011 John Wiley & Sons, Ltd

    Programa de estrategias de aula inversa para el aprendizaje de lengua y literatura, en una unidad educativa del Ecuador, 2022

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    El presente estudio tuvo como objetivo proponer un programa de estrategias de aula inversa para la enseñanza y aprendizaje de la lengua y literatura en una Unidad Educativa del Ecuador. Para ello utiliza el enfoque cuantitativo, de tipo descriptivo y propositivo, con un diseño proyectivo. El instrumento utilizado fue un cuestionario validado por juicio de expertos y la confiabilidad dada por el Alfa de Cronbach que para el instrumento fue de 0,833. La población a la que estuvo dirigida la investigación estuvo conformada por 35 estudiantes pertenecientes al segundo bachillerato “B”, la muestra utilizada fue censal. Para el tratamiento de los datos se utilizó el estadístico SPSS, que permitió organizar los resultados en tablas de frecuencias y porcentuales, para su análisis e interpretación. Los resultados obtenidos mediante el análisis descriptivo de las variables permitieron determinar que dentro del proceso de enseñanza de la lengua y literatura, no se viene utilizando técnicas y estrategias que estimulen el aprendizaje de la lengua y literatura. Se concluye en la necesidad replantear la forma de enseñar lengua y literatura y para ello se propone un programa de estrategias de aula inversa, que permita mejorar la enseñanza y aprendizaje del área curricular

    The infinity in an experiment with confronted mirrorcs

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    Se realiza un experimento de enseñanza con espejos enfrentados para comprobar la hipótesis de que los conjuntos infinitos discretos en relación de inclusión y cuyos elementos aparecen alineados, tal y como aparecen en los espejos enfrentados, son idóneos para introducir el criterio de correspondencia, tomando como agente mediador la biyección con N, como criterio de comparación de los cardinales transfinitos.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
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